The Last Laugh

Chevy Chase

Al Hart

Richard Dreyfuss

Buddy Green

Andie MacDowell

Doris Lovejoy

Kate Micucci

Jeannie

Chris Parnell

Charlie Green

George Wallace

Johnny Sunshine

Lewis Black

Max Becker

Richard Kind

Jimbo

Carol Sutton

Gayle Johnson

Amy Brassette

Stand-up Comic / Show Host

Ritchie Montgomery

Texas MC

Isla Cervelli

Courtesan

Kit Willesee

Actress in Cafe

Jason Batchko

Little Leo

Belinda D'Pree

Mary Anne

Chris Fleming

Himself

Yuka Takara

Tucson Comic

Karla Garcia

Tijuana Prostitute (uncredited)

Aaron Mitchell

Truck Stop Patron (uncredited)